Genius filmaker, Mike Figgis (Leaving Las Vegas, Timecode), brings together a dazzling all-star cast - Rhys Ifans (Notting Hill), David Schwimmer (Friends), Saffron Burrows (Deep Blue Sea), Max Beesley (Tom Jones), John Malkovich (Con Air, In the Line of Fire), Salma Hayek (Frida), Lucy Liu (Charlie's Angels, Kill Bill) in this story of dark sexual intrigue where no one is quite what they seem and the staff are more in control than the guests.

A film crew and actors arrive at the seemingly secure and beautiful Venetian hotel to film a version of the classic Jacobean tragedy, "The Duchess of Malfi".  Shadowing the production are two rival entertainment reporters (Salma Hayek and Lucy Liu) who immediately start a war of egos.  When the director (Rhys Ifans) is put out of commission, the producer (David Schwimmer) must take over the production, and that's when the cannibals and vampires start picking off the film crew and guests ...

Figgis brings a fresh approach to film-making.  Add this to the surplus of bizarre sexual activity and horrific cannibalistic images and Hotel becomse one place you will not want to check into alone ...